B2B demand generation professional are being encouraged to drive nurturing programs to develop prospects with initial interest to the point where they are ready to begin a buying process. By automating this aspect of demand generation, sales is in the position of working higher qualified leads. But getting started with this process has more complexity than just defining a nurture campaign and turning it on. If you are in a position where you are not yet using lead nurturing (you should know that you have a lot of company so don't feel like you are behind), you are probably in one of two general categories for handling leads today
1. You may have an inside sales or telemarketing group that is pre-qualifying inbound leads and setting appointments for your sales team.
2. You may be routing inbound leads directly to your sales team or distribution channel.
In either case, your sales channel is used to a certain quality and volume of leads driving their activity. If you use Option 1, you likely send a reasonable volume of leads to your sales team and find that a fair number of people are taking appointments to placate your telemarketing team but the deals don't go anywhere so you have a quality problem. If you are using Option 2, your sales team has gotten used to sifting through your leads and is probably picking out the apparent good leads and ignoring the rest.
Lead nurturing will clearly help either scenario but it will also disrupt the current volume and quality that sales is handling. So, you need to get your sales team ready for this change and find a way to redirect their effort due to less leads from marketing.
Turning all of these knobs along with defining your nurture campaigns (define the buying stages, aligning content to these stages, defining your different buyers, etc.) is not a simple process. One thing that might help is a logical way to get started with lead nurturing to help you get started and understand the impact. Here's one idea...look for more soon.
Revive Nurture - One type of nurturing is used to find lost gems in your current list. This is a great place to start as it doesn't disrupt your current lead gen processes. It simply finds some lost opportunities and drives some increased volume for your sales teams. You can run this nurture campaign by identifying contacts that have not interacted with you or responded to any of your outbound activity for a prolonged period (e.g. consider a period equal to your typical buying cycle). Contact these people to see if they are still interested in hearing from you and offer them some information. Obviously, you probably won't get a big response but you will likely drum up some opportunities.

Aprimo, like many of our customers, lives inside a crazy business. Unfortunately, many practices in our industry are counterproductive and end up hurting the customers and markets we serve. The latest glaring example of this is what is happening in the B2B demand generation space. Vendor after vendor is trying to "one up" the other guy by promising more and more success with fewer and fewer services. The latest, most glaring example, is the claim of total system success in just 5 days by one of our competitors. Frankly, we are headed to the bottom when it comes to customer service in this space.